No. 23 Indiana vs. Northwestern odds, prop bets, predictions: Hoosiers cover as double-digit favorite at Wildcats

The Indiana Hoosiers bring one of this season’s most prolific Big Ten offenses to Evanston, Illinois when they face Northwestern on Saturday.

Curt Cignetti became the first Indiana head coach to begin his tenure at 5-0 with last week’s 42-28 win over Maryland. Northwestern has struggled to score, averaging just 12.6 ppg against FBS opponents.

This looks like a complete mismatch. Let’s examine Indiana vs. Northwestern odds, prop bets, predictions, with the Hoosiers double-digit road favorites against the Wildcats on highly-rated sports betting apps.

No. 23 Indiana vs. Northwestern odds: Spread, moneyline, total for Week 6 CFB matchup

Check out live odds on Indiana vs. Northwestern at top-rated online sportsbooks.

Indiana opened as a 10.5-point favorite, but the line ballooned during early Week 6 CFB wagering. While the low total reflects Northwestern’s inability to score, Indiana has the potential to go OVER on its own.

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Indiana betting news and analysis

Indiana (5-0 SU, 4-1 ATS) is paying off at an 80% clip ATS this season. At No. 23 in the AP Top-25, the Hoosiers boast a national ranking for the first time since the start of the 2021 season.

Indiana QB Kurtis Rourke transferred in after spending five seasons at Ohio. Rourke threw for 359 yards and three passing touchdowns in the win over Maryland. It marked the 11th time he’s thrown for 3+ TDs.

Indiana has a trio of RBs in Justice Ellison, Ty Son Lawton, and Elijah Green who’ve accounted for a combined 15 rushing TDs through five games.

WRs Elijah Sarratt and Omar Cooper Jr. have both topped 300 receiving yards and added a combined five TDs. Indiana is tied with Ohio State for the Big Ten lead in ppg at 48.8.

The Hoosiers also rank 8th nationally in average margin of victory (26.3 points). Cignetti has worked his magic at Indiana after carrying James Madison to an 11-2 record last season.

Northwestern betting news and analysis

Northwestern (2-2 SU, 1-3 ATS) has scored more than 20 points in only one game this season. That was against FCS school Eastern Illinois, 31-7.

The Wildcats lost their Big Ten opener against Washington 24-5 last week. Quarterback Jack Lausch threw for just 53 yards and two picks. He also led Northwestern’s rushing “attack” with 21 yards on 13 carries.

Lausch has struggled since taking over two weeks ago. Don’t be surprised to see Vanderbilt transfer Mike Wright back under center at some point on Saturday.

Northwestern competed in a 26-20 OT loss to Duke, but it’s hard to get excited about the prospect of the Wildcats hanging with the Hoosiers in this one.

The marks the first time the two teams have played in Evanston since the 2016 season. Northwestern leads the all-time series, 47-35-1.

Northwestern has also won five of the last six meetings, but Indiana prevailed most recently in 2019 with a 34-3 victory.