Islam Makhachev will look to defend his UFC lightweight title against Dustin Poirier at UFC 302 in Newark, New Jersey on June 1.
The bout was confirmed by UFC boss Dana White following the historic UFC 300 pay-per-view in Las Vegas.
White also confirmed the return of Conor McGregor, who will take on Michael Chandler in a long-awaited grudge match at UFC 303 during International Fight Week.
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Poirier is looking to touch undisputed UFC gold for the first time, having previously held an interim title but twice fallen short when challenging for the full belt.
Makhachev has defended his 155-pound title twice, both to then-featherweight champion Volkanovski, having defeated Charles Oliveira for the vacant strap.
The native of Dagestan in Russia last fought in October when he knocked Volkanovski out via headkick.
Poirier bounced back from a headkick knockout defeat of his own at the hands of Justin Gaethje to stop the rising Benoit Saint Denis in two rounds last month.
At 35, “The Diamond” may well view this as his last chance at becoming an undisputed UFC champion.